Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولSuppression of the intrinsic apoptosis pathway by synaptic activity.
Synaptic activity promotes resistance to diverse apoptotic insults, the mechanism behind which is incompletely understood. We show here that a coordinated downregulation of core components of the intrinsic apoptosis pathway by neuronal activity forms a key part of the underlying mechanism. Activity-dependent protection against apoptotic insults is associated with inhibition of cytochrome c rele...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2009
ISSN: 1350-9047,1476-5403
DOI: 10.1038/cdd.2009.29